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. 2014 Aug 13;5(16):7198–7211. doi: 10.18632/oncotarget.2278

Figure 2. Apoptin interacts with the SH3-domain of Abl – confirmation of apoptin's interaction with BCR-ABL1.

Figure 2

(a) TransSignal SH3 Domain Array1 interaction of apoptin and SH3 domains of Abl (D 3, 4); (b) Production of recombinant GST conjugated apoptin. (c) Akt, Apoptin & Bcr-Abl Interaction: Class lb SH3 ligand specifically ‘pulls down’ its corresponding protein-protein interaction domains.