Normalized spectral response of the photodetector in its initial state, after silanization and crosslinking, after DNA immobilization with DNA containing the specific -SH termination that allows immobilization (ss-DNA-SH), and after exposure to DNA with the same base sequence without -SH termination (ss-DNA). The inset displays the signal obtained using the bio-detector and, independently, by fluorescence microscopy after immobilization of probes with and without the reactive thiol group.