Table 3. Inhibitory effects of protease inhibitors and EDTA on the lethality of crude extracts of Blarina salivary glands.

	Conc., μM	Dead/alive*	Time to death, h
Control		5/0	0.5-2.0
Aprotinin	7.8	0/3	NA
Aprotinin	3.9	3/0	2.0-3.5
Leupeptin	240	0/2	NA
Leupeptin	120	2/0	1.5-3.5
EDTA	10,000	3/0	0.5-2.0
PKSI	1,000	2/0	1.0-2.0

NA, not applicable; PKSI, plasma kallikrein specific inhibitor.

^*Mice surviving beyond 24 h were classified as “alive”