TABLE 3.
Primary infection results1
| Variable | Hypocaloric (n = 41) | Eucaloric (n = 42) | P value | OR (95% CI) |
| Total no. of infections | 82 | 66 | 0.72 | — |
| Infections per patient (n) | 2.0 ± 0.62 | 1.6 ± 0.2 | 0.50 | — |
| Any infection [% (n)]34 | 70.7 (29) | 76.2 (32) | 0.57 | 0.76 (0.28, 2.01) |
| ICU-acquired infection [% (n)]35 | 56.1 (23) | 57.1 (24) | 0.92 | 0.96 (0.40, 2.28) |
| Infection site [% (n)] | ||||
| Pneumonia | 43.9 (18) | 47.6 (20) | 0.73 | 0.86 (0.36, 2.04) |
| Central line | 4.9 (2) | 4.8 (2) | 0.98 | 1.03 (0.14, 7.65) |
| Bloodstream | 24.4 (10) | 19.1 (8) | 0.56 | 1.37 (0.48, 3.92) |
| Urinary tract | 14.6 (6) | 14.3 (6) | 0.96 | 1.03 (0.30, 3.50) |
| Wound | 12.2 (5) | 7.1 (3) | 0.44 | 1.81 (0.40, 8.10) |
| Causative organism [% (n)] | ||||
| Gram negative | 53.7 (22) | 42.9 (18) | 0.33 | 1.54 (0.65, 3.67) |
| MRSA | 2.4 (1) | 4.8 (2) | 0.58 | 0.50 (0.04, 5.74) |
| Escherichia coli | 7.3 (3) | 7.1 (3) | 0.98 | 1.03 (0.20, 5.41) |
| Anaerobe | 12.2 (5) | 9.5 (4) | 0.7 | 1.32 (0.33, 5.31) |
| Fungus | 14.6 (6) | 14.3 (6) | 0.96 | 1.03 (0.30, 3.50) |
1
Continuous variables were compared by using Student's t test and the Wilcoxon rank-sum test. Categorical variables were compared by using the Wald χ2 test and Fisher exact test. Bivariable logistic regression and the Wald χ2 test were used to estimate the relative odds of hospital-acquired infection and associated 95% CIs. ICU, intensive care unit; MRSA, methicillin-resistant Staphylococcus aureus.
2
Mean ± SE (all such values).
3
Adjusted ORs for the primary outcome were calculated by using multivariate logistic regression to control for risk of refeeding and the percentage of goal calories received.
4
Adjusted P = 0.41; OR: 0.82; 95% CI: 0.28, 2.39.
5
Adjusted P = 0.61; OR: 0.78; 95% CI: 0.31, 2.00.