Table 3c.
Significantly affected genes associated with apoptosis and DNA damage.
| Gene title | Gene symbol | p-Value | Fold-change (S vs. C)a |
|---|---|---|---|
| Apoptosis and survival_BAD phosphorylation | |||
| epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | EGFR | 0.02 | 1.59 |
| phosphoinositide-3-kinase, regulatory subunit 2 (beta) | PIK3R2 | 0.04 | 1.23 |
| protein kinase, cAMP-dependent, catalytic, gamma | PRKACG | 0.02 | 1.25 |
| protein tyrosine phosphatase, non-receptor type 11 | PTPN11 | 0.03 | − 1.11 |
| SHC (Src homology 2 domain containing)-transforming protein 1 | SHC1 | 0.03 | 1.16 |
| DNA damage_Role of SUMO in p53 regulation | |||
| CREB-binding protein | CBP | 0.01 | 1.31 |
| SMT3 suppressor of mif two 3 homolog 1 (S. cervisiae) | SUMO-1 | 0.03 | 1.17 |
| ubiquitin-like modifier activating enzyme 1 | UBA1 | 0.04 | 1.14 |
| Other genes involved in DNA damage and oxidative stress | |||
| HLA-B (major histocompatibility complex, class I, B)-associated transcript 3 | BAT3/BAG6 | 0.01 | − 1.21 |
| calpain 9 | CAPN9 | 0.05 | 1.15 |
| calpain 10 | CAPN10 | 0.02 | 1.14 |
| clusterin | CLU | 0.02 | 2.02 |
a
S = schizophrenia; C = control.