Table 5.

Overrepressented KEGG pathways based on enrichment analysis of the predicted target genes of the differentially expressed miRNAs.

Pathway	Enrichment statistics
TGF-β signaling pathway	C = 155; O = 63; E = 8.75; R = 7.20; rawP = 1.27e-37; adjP = 1.45e-35
Focal adhesion	C = 201; O = 48; E = 11.35; R = 4.23; rawP = 9.92e-18; adjP = 1.46e-16
Regulation of actin cytoskeleton	C = 143; O = 37; E = 8.07; R = 4.58; rawP = 3.41e-15; adjP = 4.32e-14
Apoptosis	C = 82; O = 20; E = 4.63; R = 4.32; rawP = 2.12e-08; adjP = 8.06e-08
ECM-receptor interaction	C = 84; O = 16; E = 4.74; R = 3.37; rawP = 1.67e-05; adjP = 4.63e-05