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. 2014 Aug 13;198(2):531–545. doi: 10.1534/genetics.114.168799

Figure 7.

Figure 7

Reduced ROS levels in high Ty1 copy strains at early time points may contribute to lifespan extension. (A) Mean of normalized dihydrorhodamine (DHR), fluorescence obtained from at least four trials of zero Ty1 copy (blue columns) and high Ty1 copy (orange columns) strains after the indicated number of days in rich medium without or with 30 mM hydroxyurea, “YPD” or “YPD + HU,” respectively. Error bars indicate standard deviation, and **P < 0.01 compares zero and high Ty1 copy strains at the indicated day. (B) As for A for three trials using synthetic medium without or with 30 mM hydroxyurea, “SC” or “SC + HU,” respectively. *P < 0.05, comparing zero and high Ty1 copy strains. (C) As for A for five trials using YPD with 30 mM hydroxyurea and incubation at 30°. (D) Mean of normalized dihydroethidium (DHE), fluorescence obtained from three trials of zero Ty1 copy (blue columns) and high Ty1 copy (orange columns) strains in synthetic medium without or with 30 mM hydroxyurea, “SC” or “SC + HU,” respectively. *P < 0.05, comparing zero and high Ty1 copy strains.