Table 1. Tests of XX sperm-only mutants for reprogramming competence.
| Genotypea | Treatment | % making oocytesb | nc |
|---|---|---|---|
| Wild type | None | 100 | NA |
| lip-1 | None | 100 | NA |
| puf-8 | None | 97 | NA |
| fbf-1 | None | 99 | NA |
| puf-8; lip-1 | None | 0 (± 0) | 135 |
| DMSO | 0 (± 0) | 85 | |
| U0126 | 97 (± 6.3) | 121 | |
| fbf-1; lip-1 | None | 0 (± 0) | 39 |
| DMSO | 0 (± 0) | 29 | |
| U0126 | 69.7 (± 4.8) | 131 | |
| puf-8 fbf-1 | None | 0 (± 0) | 609 |
| DMSO | 0 (± 0) | 641 | |
| U0126 | 0 (± 0) | 658 | |
| puf-8 fbf-1; lip-1 | None | 0 (± 0) | 70 |
| DMSO | 0 (± 0) | 190 | |
| U0126 | 0 (± 0) | 42 | |
| fem-3(gf) | None | 0 (± 0) | 193 |
| DMSO | 0 (± 0) | 659 | |
| U0126 | 0 (± 0) | 1080 | |
| mog-1 | None | 0 (± 0) | 159 |
| DMSO | 0 (± 0) | 321 | |
| U0126 | 0 (± 0) | 284 |
a
Alleles: puf-8(q725), fbf-1(ok91), lip-1(zh15), fem-3(q20), and mog-1(q151).
b
Standard deviation from mean is in parentheses.
c
n, number animals scored. NA, not applicable if numbers cited are from literature, with references as follows: wild type, Brenner (1974); lip-1, Hajnal and Berset (2002); puf-8, Bachorik and Kimble (2005); and fbf-1, Crittenden et al. (2002).