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. 2014 Oct 14;8:318. doi: 10.3389/fncel.2014.00318

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Copyright © 2014 Skardelly, Gaber, Burdack, Scheidt, Schuhmann, Hilbig, Meixensberger and Boltze.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Modulation of astrogliosis by hNPC treatment. astroglial activation patterns showed a heterogenous phenotype. There was a tendency toward reduced astroglial activity in most investigated areas in animals receiving local hNPC administration, particularly at days 28 and 84 in trauma and border zones (A,B) as well as the perilesional cortex, corpus callosum and basal ganglia (C,D). However, this difference was only statistically significant in the lesion border zone at day 84 (B). **p < 0.01.