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(a) Landmarks in neurodegeneration with brain iron accumulation (NBIA) research. (b) Davison's pallidopyramidal degeneration (PPD) triad illustrated in the form of Venn diagrams. (c) Classification of pallidopyramidal syndromes (PPS) according to age at onset and main signs and symptoms. Approximate frequency of each subtype is depicted by the size of the circle (authors’ unpublished observations). Overlapping circles indicate overlapping clinical presentations.
