Fig. 2.
miRNA-940 is the most down-regulated miRNA in TOF patients. (A) Northern blot shows that miRNA-940 is highly expressed in human heart. Shown in each lane is: 1-lung; 2-pancrease; 3-heart; 4-brain; 5-kidney; 6-skeletal muscle; 7-spleen; 8-liver; 9-bladder; 10-stomach; 11-colon; 12-intesetin. U6 was used as a loading control. (B) qRT-PCRs validate the down-regulation of miRNA-940 in an independent set of 26 TOF patients comparing to 15 healthy controls. *P < 0.05.