Table 3.

Multivariate^* cumulative relative risk of multiple skin cancers

	Age-adjusted	P-value	MV Adjusted	P-value
Skin reaction to the sun
Burn then tan	1.27 (1.18–1.36)	<0.0001	1.19 (1.11–1.28)	<0.0001
Painful burn	1.45 (1.34–1.56)	<0.0001	1.29 (1.18–1.40)	<0.0001
Number of severe sunburns
1–2 burns	0.96 (0.83–1.10)	0.56	0.94 (0.82–1.08)	0.38
3–5 burns	1.07 (0.95–1.22)	0.26	1.03 (0.91–1.16)	0.69
6–9 burns	1.19 (1.05–1.36)	0.0062	1.11 (0.98–1.26)	0.11
10+ burns	1.38 (1.23–1.55)	<0.0001	1.21 (1.07–1.36)	0.002
Family history of melanoma
Yes	1.17 (1.05–1.30)	0.006	1.15 (1.03–1.28)	0.013
Male gender
Yes	1.22 (1.18–1.27)	<0.0001	1.53 (1.40–1.66)	<0.0001
Natural hair colour
Black	0.95 (0.81–1.12)	0.56	0.95 (0.81–1.13)	0.57
Light brown	1.09 (1.02–1.17)	0.016	1.05 (0.98–1.12)	0.21
Blonde	1.21 (1.10–1.33)	<0.0001	1.12 (1.02–1.24)	0.02
Red	1.42 (1.23–1.63)	<0.0001	1.23 (1.07–1.42)	0.005
Nevi on left arm
1–2 nevi	1.11 (1.03–1.20)	0.005	1.11 (1.03–1.20)	0.005
3–5 nevi	1.14 (1.02–1.27)	0.02	1.14 (1.02–1.27)	0.025
6+ nevi	1.25 (1.09–1.43)	0.001	1.22 (1.07–1.40)	0.004

^*Multivariate regression for a given exposure of interest uses all other exposures as covariates.