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. 2014 Sep 10;53(40):6323–6331. doi: 10.1021/bi5008172

Figure 1.

Figure 1

Time course of TMR-Aβ aggregation in the presence of various forms of the apoE proteins. Panels A–C show the aggregation of TMR-Aβ1–40: (A) 4 μM TMR-Aβ1–40 in the presence of 0, 50, 100, and 200 nM recombinant lipid-free apoE4 and (B and C) 4 μM TMR-Aβ1–40 in the absence or presence of 150 nM recombinant lipid-free apoE (B) and DMPC–apoE (C), respectively. Panels D–F show the aggregation of TMR-Aβ1–42: 2 μM TMR-Aβ1–42 in the absence or presence of recombinant lipid-free apoE (50 nM), DMPC–apoE (50 nM), and astrocyte-derived apoE (11 nM) respectively.