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. 2014 Sep 10;53(40):6323–6331. doi: 10.1021/bi5008172

Figure 3.

Figure 3

Electron microscopy of the apoE–Aβ complexes. Representative images of the apoE4–Aβ1–42 solution collected (A) at time zero, (B) during the intermediate phase, and (C) during the growth phase of aggregation. The black dots represent gold nanoparticles attached to the molecules of apoE4 via a six-His tag at the N-terminus of apoE.