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Crystal structures of FABP4. (A) Solvated FABP4. Sodium (Na+) is shown as a purple sphere. Chlorine (Cl–) is shown as a green sphere. Waters are shown as lines, and oxygen is red. (B) Closed conformation of FABP4 (PDB entry 2QM9). (C) Open conformation of FABP4 (PDB entry 3HK1). Carbon atoms of the ligands are white, carbon atoms of the protein are green, oxygen is red, nitrogen is blue, and sulfur is yellow.
