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. 2004 May 10;101(20):7751–7756. doi: 10.1073/pnas.0307850101

Fig. 4.

Fig. 4.

DHPG protects OPCs from nonexcitotoxic and excitotoxic forms of oxidative stress. (A) Effect of Euk-8, Euk-134 (30 μM each), or NBQX (50 μM) on kainate-(50 μM) or OGD-(2 h) induced OPC toxicity at 24 h. (B) Effect of DHPG (100 μM), Euk-134 (30 μM), or NBQX (50 μM) on cystine deprivation-(3μM cystine) induced OPC toxicity at 24 h. (C) Dose response of the effect of DHPG on cystine deprivation-(3 μM cystine) induced OPC toxicity at 24 h in the absence or presence of the mGluR antagonist MCPG (500 μM). *, P < 0.001 vs. none.