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Difference images of averaged Mecp2-knockout (KO) vs. averaged WT 2D gels showing protein spot changes. The 2D electrophoresis and computerized comparisons were performed in OE (A and C) and OB (B and D) at the age of 2 (A and B)and4(C and D) weeks after birth. Most of the changes were observed at 2 weeks, in both OE and OB, whereas at 4 weeks after birth there were almost no differences between WT and KO tissues.
