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. 2014 Oct 14;9(10):e109569. doi: 10.1371/journal.pone.0109569

Figure 1. Alternative three-way network topologies including a Transcription Factor (TF), a Target gene (Tg) and a Modulator gene (M).

Figure 1

(A) depicts the independent regulation of the target gene by a modulator and a TF; (B) describes a three-way interaction between the TF, the target gene and the modulator.