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. 2014 Oct 14;9(10):e109771. doi: 10.1371/journal.pone.0109771

Figure 1. Correlation between charged amino acids at Env positions 322/440 in phenotypically characterized B-HIV strains.

Figure 1

(A) Values represent the percentage of Envs that have the indicated type of amino acid (+, positively charged; -, negatively charged; o, neutral) at position 440 out of all Envs with the indicated type of amino acid at position 322. Subscript values represent the percentage of R5 or CXCR4-using Envs that have the indicated combination of amino acid types at positions 322/440. (B) Values represent the percentage of R5 or CXCR4-using Envs that have the combination of indicated amino acids at Env positions 322/440. Amino acids are colored according to charge; positively charged (+, Arg and Lys) in blue, negatively charged (-, Asp and Glu) in red and neutral (o) in white. 322/440 amino acid combinations are colored according to charge; +322/+440 in dark blue, −322/−440 in dark red, +322/−440 or −322/+440 in purple, +322/o440 or o322/+440 in light blue, −322/o440 or o322/−440 in light red and o322/o440 in white. P-values were calculated by chi-square analysis.