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. 2014 Oct 14;9(10):e109771. doi: 10.1371/journal.pone.0109771

Figure 2. Nucleotide codon usage of R5 and CXCR4-using B-HIV Envs at position 440.

Figure 2

The size of each node indicates the relative frequency of the indicated nucleotide codon. A black line connects codons separated by one nucleotide substitution. Codons encoding positively charged amino acids at colored blue, codons encoding negatively charged amino acids are colored red and codons encoding neutral amino acids are colored white. Nucleotide codons at position 440 were aligned and analysed using CLC Main Workbench version 6.5. 75 CXCR4-using (46 R5X4 and 29 X4) and 293 R5 sequences were analyzed.