Table 2. Frequencies of ALDH2 genotypes and alleles in IS patients and PSE patients.
Genotype | IS | PSE | ORa |
Overall subjects | (n = 240) | (n = 225) | |
GG | 156 (65.0%) | 109 (48.4%) | 1.00 (reference) |
GA | 66 (27.5%) | 89 (39.6%) | 1.98 (1.36∼2.87)a |
AA | 18 (7.5%) | 27 (12%) | |
Negative history of drinking | |||
GG | 106 (59.9%) | 65 (38.7%) | 1.00 (reference) |
GA | 56 (31.6%) | 80 (47.6%) | 2.37 (1.54∼3.65)b |
AA | 15 (8.5%) | 23 (13.7%) | |
Positive history of drinking | |||
GG | 50 (79.3%) | 44 (77.2%) | 1.00 (reference) |
GA | 10 (15.9%) | 9 (15.8%) | 1.14 (0.48∼2.71) |
AA | 3 (4.8%) | 4 (7.0%) |
Adjusted for age, sex, hypertension, BMI, and drinking.
P = 0.00036,
P = 0.00010.