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. 2014 Oct 14;9(10):e110002. doi: 10.1371/journal.pone.0110002

Figure 8. Effect of preventive treatment with SmSWP on inflammatory parameters.

Figure 8

Effect on clinical disease score (A), body weight (B), colonoscopic score (C), macroscopic inflammation score (D), colon length (E), microscopic inflammation score (F) and MPO activity (G). Data are presented as mean ± SEM. Generalized Estimations Equations was used to analyze the evolution of the body weight, the clinical disease score and colonoscopic score over time and an LSD post-hoc analysis was applied. One-way ANOVA with LSD post-hoc test was used to compare the results of macroscopic and microscopic scores, colon length and MPO activity between groups. #: P≤0.05, significantly different from CONTROL group; *: P≤0.05, significant difference between the COLITIS and COLITIS+prevSmSWP groups; §: P≤0.05, significant increase in score over time within groups; “n” representing the number of mice. Abbreviations: LSD: least significant difference; MPO: myeloperoxidase; prev: preventive; SEM: standard error of the mean; SmSWP: Schistosoma mansoni soluble worm proteins.