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. 2014 Oct 14;9(10):e110002. doi: 10.1371/journal.pone.0110002

Table 1. Cytokine profile in serum measured by CBA.

CONTROL COLITIS COLITIS+curSmSWP COLITIS+prevSmSWP
CBA serum (pg/ml)
IL-2 0.0±0.0 0.8±0.3# 0.5±0.2 0.3±0.1
IFN-γ 0.0±0.0 22.6±8.8 38.6±19.3# 17.5±6.9
TNF 3.0±0.6 83.6±12.5# 79.7±19.4# 75.0±11.5#
IL-6 0.0±0.0 8.1±1.8# 7.9±2.4# 4.5±1.0
IL-17A 1.4±0.7 6.1±0.8 4.8±1.5 14.7±5.8# , *
IL-4 0.0±0.0 0.0±0.0 0.6±0.6 0.0±0.0
IL-10 2.7±0.9 3.7±0.8 3.8±0.8 2.3±0.9

Data are presented as mean ± SEM. One-way ANOVA with LSD post-hoc test was used to compare the results between the CONTROL, COLITIS and COLITIS+curSmSWP groups or between CONTROL, COLITIS and COLITIS+prevSmSWP groups.

#

: P≤0.05, significantly different from CONTROL group;

*: P≤0.05, significant difference between COLITIS and COLITIS+prevSmSWP groups. N = 9–12 per animal group. Abbreviations: CBA: cytometric bead array; cur: curative; IFN-γ: interferon-γ; IL: interleukin; prev: preventive; SmSWP: Schistosoma mansoni soluble worm proteins; TNF: tumor necrosis factor.