Table 1. Parameter values and their definitions.
Parameter | Interpretation | Value | Reference |
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Rate of progression from acute to chronic HBV infection | 0.4/person/year | [16], [19], [23] |
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Rate of partner change | 1.64 partners/year (![]() |
[16] |
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Death rate in population | 0.007/year | [42] |
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Vaccination coverage in children immediately after birth | 0.9 (![]() |
[21], [42] a |
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Probability of passing HBV infection from mother to child during birth | 0.9 (![]() |
[22] |
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Recovery rate of adults from acute HBV infection | 3.6/person/year | [16], [19], [23] |
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Probability of HBV transmission from an individual in the HBV acute phase | 0.46 | [16], [23] |
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Probability of HBV transmission from an individual in the HBV chronic phase | 0.65![]() |
[16], [23] |
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Rate of progression from acute to chronic in dually infected | 2/person/year | [16], [23] |
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Recovery rate of adults from acute dual infection | 2/person/year | [16], [23] |
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Probability of HBV transmission from dually infected individual at stage ![]() |
0.71 | [16], [43] |
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Probability of HDV transmission from dually infected individual at stage ![]() |
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[16] |
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Disease induced mortality rate in chronically HBV infected individuals | 0.0013/year | [7]–[9] |
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Disease induced mortality rate in chronic dual infection | 0.013/year | [7]–[9] |
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Rate of maturation to adult aged 14+ years for uninfected children and children born with HBV | 1/14/year (![]() |
[44] |
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Extra-mortality rate during childhood (for China) | 0.01/year | [42] |
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Rate of growth of population in China | 0.019/year | [42] |
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Maximum Carrying Capacity of the population in China | 3.8e+09 |
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Adult vaccination coverage | 0/year |
avaccination started in China in 1992 with a coverage of 20%. In 2003, vaccination coverage reached 90% and continued to increase. We assumed it to be a constant coverage of 90% from the beginning of the vaccination programs.
bobtained after fitting the total population (using non-linear least squares and assuming logistic growth) to population data in China from [45], for the period 2003–2011. This procedure reproduced the data of the total population well.