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. 2014 Oct 14;9(10):e110143. doi: 10.1371/journal.pone.0110143

Table 1. Parameter values and their definitions.

Parameter Interpretation Value Reference
Inline graphic Rate of progression from acute to chronic HBV infection 0.4/person/year [16], [19], [23]
Inline graphic Rate of partner change 1.64 partners/year (Inline graphic) [16]
Inline graphic Death rate in population 0.007/year [42]
Inline graphic Vaccination coverage in children immediately after birth 0.9 (Inline graphic) [21], [42] a
Inline graphic Probability of passing HBV infection from mother to child during birth 0.9 (Inline graphic) [22]
Inline graphic Recovery rate of adults from acute HBV infection 3.6/person/year [16], [19], [23]
Inline graphic Probability of HBV transmission from an individual in the HBV acute phase 0.46 [16], [23]
Inline graphic Probability of HBV transmission from an individual in the HBV chronic phase 0.65Inline graphic [16], [23]
Inline graphic Rate of progression from acute to chronic in dually infected 2/person/year [16], [23]
Inline graphic Recovery rate of adults from acute dual infection 2/person/year [16], [23]
Inline graphic Probability of HBV transmission from dually infected individual at stage Inline graphic = 1,2 0.71 [16], [43]
Inline graphic Probability of HDV transmission from dually infected individual at stage Inline graphic = 1,2 Inline graphic [16]
Inline graphic Disease induced mortality rate in chronically HBV infected individuals 0.0013/year [7][9]
Inline graphic Disease induced mortality rate in chronic dual infection 0.013/year [7][9]
Inline graphic Rate of maturation to adult aged 14+ years for uninfected children and children born with HBV 1/14/year (Inline graphic) [44]
Inline graphic Extra-mortality rate during childhood (for China) 0.01/year [42]
Inline graphic Rate of growth of population in China 0.019/year [42]
Inline graphic Maximum Carrying Capacity of the population in China 3.8e+09 Inline graphic
Inline graphic Adult vaccination coverage 0/year

avaccination started in China in 1992 with a coverage of 20%. In 2003, vaccination coverage reached 90% and continued to increase. We assumed it to be a constant coverage of 90% from the beginning of the vaccination programs.

bobtained after fitting the total population (using non-linear least squares and assuming logistic growth) to population data in China from [45], for the period 2003–2011. This procedure reproduced the data of the total population well.