Figure 5. ClC-7^td mice lack a coat colour phenotype.

A Clcn7^td/td mice are brown contrasting with the grey fur of Clcn7^−/− mice.

B Upper panels: pheomelanin granules clump in hair shafts of Clcn7^−/− and Ostm1^−/− but not in Clcn7^unc/unc, Clcn7^td/td and WT mice. Normally distributed eumelanin granules in the dark hair shafts of all mouse models (lower panels).