Skip to main content
. 2014 Oct 14;9(10):e110580. doi: 10.1371/journal.pone.0110580

Figure 3. Cardiomyocytes ultrastructure changes as evaluated by transmission electron microscopy.

Figure 3

Cardiomyocytes mitochondria size and the destruction of cristae (magnification: medial panel×20500; lower panel×43000) after H/R (9 h/2 h) injury in HG/HF (high glucose/high fat, 25 Mm glucose, and 500 uM sodium palmitate) conditions were shown (A). ATP content and citratesynthase activity in neonatal mouse ventricular myocytes (B, C). Enzymatic activities of complexes I–V were determined in mitochondria isolated from neonatal mouse ventricular myocytes (D). Columns and bars represent mean ± SD. Data were obtained from at least three independent experiments.*p<0.05 vs. H/R, #p<0.05 vs. H/R+Lin28a.