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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Future Oncol. 2014 Jun;10(8):1487–1500. doi: 10.2217/fon.14.29

Figure 1. Structural polymorphism in CagA.

Figure 1

Western-type CagA contain the EPIYA-A, EPIYA-B and EPIYA-C segments, whereas east Asian-type CagA contain the EPIYA-A, EPIYA-B and EPIYA-D segments. EPIYA-motif in each segment represent the tyrosine phosphorylation sites of CagA. The asterix means that the nucleotide sequences are the same between western-type CagA and east Asian-type CagA.