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Expired minute ventilation (VE) corrected for body surface area (BSA), as a function of the partial pressure of end-tidal CO2 (PETCO2) (top panel) or end-tidal O2 (PETO2) (bottom panel). Each data point represents the average value computed during room air breathing and at each of three levels of hypercapnia and two levels of hypoxia in each of the subjects (see Methods).
