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. Author manuscript; available in PMC: 2016 Mar 19.
Published in final edited form as: Oncogene. 2014 Apr 14;34(12):1542–1552. doi: 10.1038/onc.2014.89

Figure 2. Mutation cluster regions (MCRs) ofδ-catenin coding sequences in human prostate cancer.

Figure 2

(A). Schematic illustration of MCRs in δ-catenin coding region. The entire coding region of δ-catenin gene was sequenced. Recurrent and non-recurrent mutations were identified. Shown here are mutations in exons 10, 13, 14, 19, 21, and 22 (recurrent) as well as 20 (non recurrent). No mutations were observed from exons 1 to 9. (B-G). Sequence chromatograms showing examples of somatic δ-catenin exon mutations. Some mutations lead to the disruption of protein sequences. Note: The lower panels indicate the tumor and the upper panels indicate the matched normal control.