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. Author manuscript; available in PMC: 2015 Apr 10.
Published in final edited form as: Nat Commun. 2014 Oct 10;5:5155. doi: 10.1038/ncomms6155

Figure 2.

Figure 2

Loss-of-function mutation of slo-2 reduced the amplitude of a spontaneous up-state in motor neurons. A. Samples traces of spontaneous membrane voltage changes of VA5 from wild type (WT), slo-2(nf101), and slo-2(nf101) rescued by expressing wild-type SLO-2b under the control of Prab-3. B. Comparisons of the resting membrane potential (RP), and up-state (US) frequency, duration, amplitude, and potential. Both the averaged value of each experiment (filled circle) and the mean ± SE of the group (line and bar) are shown. The asterisk (*) indicates a statistically significant difference compared with WT (p < 0.05, one-way ANOVA with Tukey’s post hoc tests). The sample size (n) was 15 for WT, 12 for slo-2, and 8 for Rescue. Samples without obvious up-states (4 WT and 2 slo-2 mutant) were not included in the up-state quantifications. The recordings were performed with extracellular solution I and pipette solution I.