Figure 4.
Postsynaptic receptor sensitivities and ePSCs were normal in slo-2(nf101). A. Comparison of muscle cell response to pressure-ejected acetylcholine (ACh, 100 μM) or GABA (100 μM) between wild type (WT) and slo-2(nf101). B. Comparison of ePSC between WT and slo-2(nf101) in the presence of two different extracellular Ca2+ concentrations (5 mM and 0.5 mM). Data are shown as mean ± SE. No significant difference was detected (unpaired t-test). The holding voltage was −60 mV in all the experiments. The numbers inside the columns indicate the sample sizes (n). All the recordings were performed with pipette solution I. The recordings of ePSC at 0.5 mM [Ca2+]o were performed with extracellular solution II whereas the remaining recordings were recorded with extracellular solution I.
