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Determination of HBV subtypes and mutations in MHR of HBsAg from HBsAg negative patients. (A) Pre and Post indicate the biopsy samples obtained before and after the HBsAg loss, respectively. The time interval between Pre and Post is about 3 to 5 years. The 'a'-determinant is represented in bold and rare mutations are capitalized. (B) Phylogenetic analysis of the amino acid sequences in HMR region of HBsAg.
