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Hepatic Necrosis. Twenty-year-old female with acute myeloid leukemia, on COAP regimen (cyclophosphamide, oncovin, arabinosyl cytosine and prednisone). Post treatment course was complicated by increase in liver enzymes. (A) The pretreatment image shows no abnormality in liver (B) (C) After chemotherapy, coronal (B) and axial (C) contrast enhanced CT images demonstrate focal liver necrosis vs peliosis-centrilobular hemorrhagic necrosis of the liver (arrows).
