FIG. 2.

EKIT spectrum of human calf skeletal muscle. a: A typical T2w MR image acquired from human calf using a partial volume coil. Abbreviations: Sol, soleus; GM, gastrocnemius medial; GL, gastrocnemius lateral. b: The EKIT spectrum illustrated here reflects the intensity of PCr signal plotted as a function of frequency of the inversion pulse (150 different frequencies) acquired from calf of a 25 yr healthy female with a BMI = 22.2 kg/m². Other ³¹P MRS acquisition parameters: TR 5 second, t_d 1 second, scan time 12.5 min. Note that PCr magnetization is attenuated after inversion of either γ ATP (white arrow) or β ATP (insert). c: A conventional ³¹P MR spectrum acquired showing the full chemical shift region of calf muscle ³¹P resonances, with the chemical shift aligned with that of sweeping inversion pulse used in the EKIT spectrum b.