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. 2014 Oct 4;13:138. doi: 10.1186/s12933-014-0138-3

Table 2.

Correlation of endothelial biomarkers and characteristics of the study population

sICAM-1 sVCAM-1 sE-selectin
n r p-value n r p-value n r p-value
age 140 0.05 n.s. 140 0.04 n.s. 136 0.09 n.s.
BMI 136 0.25 0.004 136 0.21 0.016 132 0.35 <0.001
RRS 131 0.14 n.s. 131 0.10 n.s. 128 0.12 n.s.
RRD 131 0.11 n.s. 131 0.18 0.036 128 0.13 n.s.
SI (FSIGT)* 133 −0.23 0.009 133 −0.22 0.011 129 −0.21 0.018
OGIS (OGTT)* 137 −0.18 0.033 137 −0.23 0.007 133 −0.12 n.s.
ΔAIRg (FSIGT)* 133 −0.09 n.s. 133 0.04 n.s. 129 −0.04 n.s.
IGI (OGTT)* 139 −0.12 n.s. 139 0.03 n.s. 135 −0.10 n.s.
Total-Cholesterol 140 −0.03 n.s. 140 0.10 n.s. 136 −0.02 n.s.
LDL-Cholesterol 137 0.08 n.s. 137 0.13 n.s. 133 0.02 n.s.
HDL-Cholesterol 140 −0.30 0.001 140 0.06 n.s. 136 −0.16 n.s.
ln(Triglycerides) 140 0.12 n.s. 140 −0.02 n.s. 136 0.12 n.s.
ln(usCRP) 116 0.28 0.003 116 0.18 n.s. 114 0.04 n.s.
ln(IL-6) 93 0.13 n.s. 93 0.16 n.s. 94 0.24 0.019
ln(PAI-1) 132 0.29 <0.001 132 0.08 n.s. 128 0.21 0.016
Fibrinogen 140 0.25 0.003 140 0.04 n.s. 136 0.25 0.003

Data are number of observarion (n) and correlation coefficients (r). BMI (body mass index), RRS (systolic blood pressure), RRD (diastolic blood pressure), SI (insulin sensitivity index derived from the FSIGT), OGIS (oral glucose tolerance index derived from the OGTT), ΔAIRG (acute insulin response to glucose derived from the FSIGT), IGI (insulinogenic index), HDL (high density lipiprotein), LDL (low density lipoprotein), usCRP (ultrasensitive C-reactive protein), IL-6 (interleukin-6), PAI-1 (plasminogen activator inhibitor 1).

*Spearman’s rank correlation as used instead of Pearson’s product moment correlation due to nonlinear monotonic associations or outliers.