Figure 2.

Age-related changes in gene expression in the mouse hippocampus. Summary of the 35 genes most significantly changed in expression between young (2 months) and middle-aged (15 months) mice. The genes are listed in order of increasing P-value. Each gene is visualized as a row of colored squares, with one square for each sample. The color indicates the relative expression of the gene according to the scale bar, with lighter colors indicating higher levels of expression. Expression levels ±2 SD from the mean of the gene are depicted as white and black, respectively. Note that the majority of genes listed showed increased expression with age. Annotations for each gene and the Welch t-test P-value (uncorrected for multiple testing) are shown at the right of the figure.