Table 2.
Baseline and 6 months 2D echocardiographic data on SAVR vs TAVI patients
| SAVR (n = 45) | TAVI (n = 42) | SAVR vs TAVIp-value | |||
|---|---|---|---|---|---|
| mean ± SD | Me (P25-P75) | mean ± SD | Me (P25-P75) | ||
| AV annulus (cm) | |||||
| Baseline | 21.34 ± 2.18 | 21 (20 - 22.75) | 20.73 ± 2.39 | 21 (19 - 22) | 0.337b |
| AV peak velocity (cm/sec) | |||||
| Baseline | 4.81 ± 0.60 | 4.76 (4.36 - 5.13) | 4.76 ± 0.61 | 4.81 (4.36 - 5.16) | 0.909b |
| 6 months | 2.69 ± 0.74 | 2.51 (2.21 - 3.00) | 2.07 ± 0.51 | 2.11 (1.72 - 2.31) | <0.001a |
| p-value* | <0.001 | <0.001 | |||
| AV mean gradient (mmHg) | |||||
| Baseline | 57.89 ± 13.91 | 54.9 (47.13 - 66.45) | 54.67 ± 15.77 | 52.5 (44.0 - 60.3) | 0.317a |
| 6 months | 17.21 ± 12.05 | 13.9 (11 - 21) | 8.86 ± 4.72 | 8.1 (5.7 - 11.4) | <0.001a |
| p-value** | <0.001 | <0.001 | |||
| AVA (EOA, cm2) | |||||
| Baseline | 0.69 ± 0.2 | 0.7 (0.52 - 0.83) | 0.62 ± 0.15 | 0.6 (0.51 - 0.7) | 0.070a |
| 6 months | 1.5 ± 0.42 | 1.4 (1.2 - 1.75) | 1.95 ± 0.54 | 1.8 (1.5 - 2.2) | <0.001a |
| p-value** | <0.001 | <0.001 | |||
| AVA index (EAOI cm2/m2) | |||||
| Baseline | 0.40 ± 0.11 | 0.38 (0.32 - 0.47) | 0.37 ± 0.1 | 0.37 (0.31 - 0.42) | 0.229b |
| 6 months | 0.87 ± 0.24 | 0.82 (0.68 - 1.00) | 1.16 ± 0.39 | 1.05 (0.88 - 1.36) | <0.001a |
| p-value* | <0.001 | <0.001 | |||
| Δ EAOI (cm2/m2) | 0.47 ± 0.28 | 0.46 (0.3 - 0.59) | 0.79 ± 0.37 | 0.65 (0.55 - 1.03) | <0.001a |
| PPM [n (%)] | 24 (58.6) | 9 (23.1) | <0.001 | ||
| Severe PPM [n (%)] | 7 (17.1) | 0 | 0.012 | ||
| Paravalvular AR 6m [n (%)] | 3 (6.7) | 23 (59) | <0.001 | ||
| E/ A ratio | |||||
| Baseline | 0.79 ± 0.34 | 0.72 (0.61 - 0.89) | 1.38 ± 0.87 | 1.07 (0.74 - 1.74) | <0.001b |
| 6 months | 0.85 ± 0.25 | 0.81 (0.69 - 0.93) | 1.34 ± 1.22 | 0.73 (0.57 - 1.74) | 0.703b |
| p-value* | 0.044 | 0.212 | |||
| E - wave deceleration time (ms) | |||||
| Baseline | 235.11 ± 73.97 | 240 (180 - 280) | 207.69 ± 79.97 | 198 (148 - 238.5) | 0.039b |
| 6 months | 264.51 ± 72.84 | 250 (218.5 - 300) | 251.82 ± 66.02 | 260 (190 - 295) | 0.755b |
| p-value* | <0.001 | <0.001 | |||
| IVRT (ms) | |||||
| Baseline | 99.09 ± 26.85 | 100 (80 - 120) | 73.4 ± 33.91 | 70 (50 - 100) | 0.001a |
| 6 months | 116.43 ± 20.41 | 110 (100 - 130) | 102.19 ± 28.93 | 100 (82.5 - 127.5) | 0.034a |
| p-value** | 0.049 | <0.001 | |||
| e’ (cm/s) | |||||
| Baseline | 4.77 ± 1.8 | 4.4 (3.6 - 5.8) | 5.56 ± 2.55 | 5 (4.1 - 6.1) | 0.157b |
| 6 months | 5.59 ± 1.52 | 5.4 (4.6 - 6.73) | 7 ± 3.07 | 6.1 (4.78 - 8.7) | 0.033a |
| p-value* | 0.005 | 0.495 | |||
| E/ e’ | |||||
| Baseline | 18.62 ± 7.11 | 16.9 (13.27 - 23.68) | 23.55 ± 10.88 | 25.36 (15.99 - 30.78) | 0.024b |
| 6 months | 16.73 ± 5.96 | 15.75 (13.02 - 19.86) | 16.36 ± 10.77 | 11.72 (8.33 - 23.06) | 0.153b |
| p-value* | 0.096 | 0.177 | |||
AV = aortic valve; AVA = aortic valve area; EAOI = effective orifice area index; Δ EAOI = absolute increase in EAOI; PPM = patient-prosthesis mismatch; IVRT = Isovolumetric relaxation time; 6m = six months; values are mean ± SD or median (P25-P75) or n (%). a,b – different letters stand for significant differences in mean or median values according to t-test (a) or the Mann–Whitney U test (b).*Wilcoxon test; **Paired-sample t-test.