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. 2014 Sep 29;14:365. doi: 10.1186/1472-6882-14-365

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© Kim et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of ISSE on the recruitment of inflammatory cells to lung tissue (A) and mucus production (B). Histological examination of lung tissues was performed 48 h after the final OVA challenge. Lung tissues were stained with H&E (A) and PAS (B). NC, negative control (PBS only); OVA, OVA-sensitized/challenged mice; Mon, montelukast (30 mg/kg) + OVA-sensitized/challenged mice; ISSE-100, ISEE (100 mg/kg) + OVA-sensitized/challenged mice; ISSE-200, ISEE (200 mg/kg) + OVA-sensitized/challenged mice.