Table 3.
Three-year risk of cardiovascular disease according to AKI stage, Northern Denmark, 2005 to 2010
| Without AKI | AKI stage 1 | AKI stages 2-3 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Events, n | Cumulative risk % (95% CI) | Events, n | Cumulative risk % (95% CI) | Unadjusted HR (95% CI) | Adjusted HR a (95% CI) | Events, n | Cumulative risk % (95% CI) | Unadjusted HR (95% CI) | Adjusted HR a (95% CI) | |
| HF | 320 | 2.2 (2.0–2.5) | 114 | 5.0 (4.2–6.0) | 2.43 (1.96–3.01) | 1.33 (1.06–1.66) | 91 | 5.0 (4.0–6.1 | 2.53 (2.01–3.01) | 1.45 (1.14–1.84) |
| MI | 135 | 1.0 (0.8–1.2) | 38 | 1.8 (1.3–2.4) | 1.93 (1.35–2.76) | 1.04 (0.71–1.51) | 40 | 2.3 (1.7–3.1) | 2.68 (1.88–3.82) | 1.51 (1.05–2.18) |
| Stroke | 131 | 0.9 (0.8–1.1) | 35 | 1.7 (1.2–2.4) | 1.83 (1.26–2.65) | 1.10 (0.75–1.62) | 26 | 1.4 (1.0–2.1) | 1.79 (1.17–2.72) | 1.07 (0.70–1.65) |
aAdjusted for age, gender, other ischemic heart diseases, other cerebrovascular diseases, hypertension, peripheral vascular disease, diabetes, chronic kidney disease, cancer, surgical status, primary diagnosis during current hospitalization, and preadmission use of drugs listed in Table 2. AKI, acute kidney injury; CI, confidence interval; HF, heart failure; HR, hazard ratio; ICU, intensive care unit; MI, myocardial infarction; n, number.