Table 4. Baseline characteristics of heart failure patient cohorts.
| Heart failure patients | HFGR | LEITZARAN | HULL LIFELAB | TIME-CHF |
| Number of patients | 218 | 233 | 3239 | 622 |
| Women, No. (%) | 59 (27) | 109 (46) | 1068 (33) | 253 (40.7) |
| Age, years | 67±13 | 74±9 | 71±11 | 77±8 |
| Body mass index, kg/m2 | 28.7±5.6 | 31.3±5.3 | 29.2±6.0 | 25.6±4.4 |
| Weight, kg | 82.6±19.2 | 79.4±16.3 | 82.4±19.3 | 72.0±14.2 |
| Height, cm | 171±10 | 159±10 | 168±10 | 167±9 |
| Smokers, No. (%) | NA | NA | 300 (9) | 74 (12) |
| Consume alcohol, No. (%) | NA | 18 (8) | 1179 (36) | NA |
| Hypertension, No. (%) | 92 (42) | 233 (100) | 1115 (35) | 462 (74) |
| Diabetes mellitus, No. (%) | 75 (34) | 0 (0) | 784 (24) | 222 (36) |
| Heart failure, No. (%) | 218 (100) | 233 (100) | 2306 (71) | 622 (100) |
| Systolic blood pressure, mmHg | 121±22 | 148±24 | 137±25 | 122±20 |
| Diastolic blood pressure, mmHg | 68±11 | 85±13 | 79±14 | 72±12 |
| Heart rate, beats per minute | 72±14 | 79±20 | 74±17 | 76±14 |
| Cholesterol, mmol/L | 4.0±1.2 | 5.2±1.8 | 4.4±1.3 | 4.2±1.1 |
| Glucose, mmol/L | 8.0±3.3 | 6.0±1.7 | 6.8±2.9 | 6.7±2.4 |
| Hemoglobin, g/dL | 13.0±1.9 | 14.0±1.5 | 13.3±3.7 | 13.1±1.8 |
| Red blood cell count, 1012 cells/L | NA | 4.6±0.47 | NA | 4.3±0.60 |
| White blood cell count, 109 cells/L | 7.7±2.7 | 7.0±1.8 | 7.6±2.8 | 7.8±4.9 |
| Platelets, 109 cells/L | 223±71 | 223±58 | 242±95 | NA |
| Creatinine, μmol/L | 111.2±34.8 | 96.4±33.8 | 105.7±50.6 | 115.9±38.4 |
| BNP, pg/mL | NA | NA | NA | NA |
| NT-proBNP, pg/mL | NA | NA | 880 (279–2088) | 3836 (1919–6895) |
| Left ventricular mass, g | NA | 270.6±115.8 | 271.6±116.0 | NA |
| Left ventricular ejection fraction, % | 35±12 | 55±16 | 41±14 | 35±13 |
| Proportion with LVEF <40% | 70 (65) | 24 (17) | 880 (51) | 402 (65) |
| Proportion with LVEF 40–50% | 20 (19) | 21 (15) | 360 (21) | 108 (17) |
| Proportion with LVEF >50% | 17 (16) | 96 (68) | 481 (28) | 112 (18) |
| E/A ratio | NA | 0.90±0.46 | 1.1±0.85 | NA |
Data are reported as number (%), mean±SD or median (25th–75th) for non-normally distributed data.
NA: data not available within the cohort