Table 3. Multivariate analysis of clinicopathologic factors in the primary cohort of 152 AML patients.

Variable	RFS (n = 38)		OS (n  =  151)
	HR (95%CI)	P	HR (95%CI)	P
Age (60–69 years vs. 70–79 years vs. ≧80 years)	0.631 (0.176–2.266)	0.480	0.779 (0.342–1.773)	0.552
WBC at diagnosis (≦30×10 ˆ9/L vs. >30×10 ˆ9/L)	0.226 (0.025–2.015)	0.183	0.971 (0.353–2.677)	0.955
LDH at diagnosis (≦250 U/L vs. >250 U/L, ≦1,000 U/L vs. > 1,000 U/L)	1.338 (0.421–4.248)	0.621	1.078 (0.535–2.172)	0.833
BM blasts at diagnosis (≧20%, ≦50% vs. >50%, ≦80% vs. > 80%)	3.747,5 (1.028–13.662)	0.045	1.676 (0.984–2.854)	0.057
Cytogenetics (good and intermediate vs. poor)	n.d.*		1.879 (0.842–4.195)	0.124
CEBPα (mutated vs. unmutated)	5.084 (0.385–67.147)	0.217	4.173 (0.918–18.966)	0.064

^*Due to the high number of missing values, this variable could not be included in the model for RFS.