Table 2.

Transcription factors in skeletal muscle potentially responsive to rehabilitation strategies

Factor	Description
Myo D	Transcriptional regulatory protein, induced during muscle regeneration(66 )
Myogenic factor 5 (Myf5)	Transcriptional regulatory protein induced during muscle regeneration(67–69)
Mechano growth factor (MGF)	A splice variant of IGF-I that leads to muscle hypertrophy via activation of satellite cells(70)
Myogenic regulatory factor 4 (Mrf4)	Myogenic regulatory factor induced during muscle regeneration(71–73)
Myogenin	Myogenic regulatory factor induced during muscle regeneration(74–76)
Transforming growth factor beta (TGF-beta)	Considered a key signaling molecule in cardiac hypertrophy and failure, among others (77–79)
IGF-1 (Insulin-like growth Factor-1)	Implicated in the control of skeletal muscle growth, differentiation, survival, and regeneration, and considered a promising therapeutic agent in staving off the advance of muscle weakness (80–84)