Table 2.
Time Interval Analysis
| AFB (N=101) |
Xpert (N=327) |
P-value | |||
|---|---|---|---|---|---|
| N | Median (IQR) | N | Median (IQR) | ||
| All participants | |||||
| Specimen transport to lab | 76 | 0.2 (0.2 – 0.4) | 306 | 0.3 (0.2 – 0.9) | 0.26 |
| Laboratory processing | 83 | 0.2 (0.2 – 0.3) | 327 | 1.6 (1.3 – 2.6) | < 0.001 |
| Result transfer to clinic | 95 | 2.2 (1.1 – 4.1) | 172 | 3.9 (2.4 – 5.5) | < 0.001 |
| Total diagnostic time* | 90 | 3.3 (2.1 – 5.2) | 156 | 6.4 (5.3 – 8.1) | < 0.001 |
| Laboratory-confirmed pulmonary TB | |||||
| Specimen transport to lab | 19 | 0.2 (0.2 – 0.4) | 117 | 0.3 (0.2 – 0.9) | 0.33 |
| Laboratory processing | 20 | 0.3 (0.2 – 0.5) | 124 | 1.6 (1.4 – 2.1) | < 0.001 |
| Result transfer to clinic | 26 | 2.0 (1.2 – 3.7) | 82 | 3.9 (2.6 – 5.6) | 0.03 |
| Total diagnostic time* | 26 | 2.4 (2.1 – 4.0) | 77 | 6.3 (5.2 – 8.2) | <0.001 |
| Sensitivity Analyses | |||||
| Total diagnostic time* (All time intervals) | 72 | 3.3 (1.4 – 5.2) | 156 | 6.4 (5.3 – 8.1) | <0.001 |
| Total diagnostic time* (Same day AFB/Xpert) | 56 | 3.2 (1.9 – 4.6) | 74 | 6.3 (5.2 – 7.2) | <0.001 |
*
Total diagnostic time was only calculated for participants who had data on the time of sputum specimen collection and the time a clinician received a test result.