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. 2014 Oct 15;4:6625. doi: 10.1038/srep06625

Table 2. Univariate and multivariate analysis of prognostic factors in HCC for disease-free survival.

  Univariate analysis Multivariate analysis
  HR p > |z| 95% CI HR p > |z| 95% CI
MAGE-A9 expression            
High versus Low 3.39 0.001* 1.898–6.046 2.54 0.006* 1.299–4.954
Gender            
Male versus Female 1.08 0.648 0.580–2.403      
Age (years)            
<60 versus ≥60 1.66 0.146 0.838–3.285      
Tumour size (cm)            
>5 versus ≤5 1.83 0.031* 1.057–3.177 1.44 0.255 0.768–2.707
α-fetoprotein status            
High versus Low 1.01 0.971 0.603–1.692      
Hepatitis B virus infection            
Positive versus Negative 1.21 0.486 0.699–2.128      
Liver cirrhosis            
Positive versus Negative 0.89 0.660 0.522–1.509      
Pathological grade            
Grade 1 and 2 versus Grade 3 0.45 0.007* 0.252–0.807 0.74 0.378 0.384–1.438
Portal vein invasion            
Positive versus Negative 3.26 0.001* 1.930–5.520 1.79 0.073 0.948–3.368
Lymph node metastasis            
Positive versus Negative 2.67 0.001* 1.548–4.605 2.29 0.008* 1.238–4.229
Distant metastasis            
Positive versus Negative 2.52 0.035* 1.068–5.966 0.60 0.317 0.216–1.644
TNM stage            
Stage I-II versus Stage III-IV 0.32 0.001* 0.184–0.565 0.77 0.480 0.370–1.598
MAGE-A9 expression+ α-fetoprotein status            
Both high versus Others situations (High + Low or Low + High or Both low) 1.60 0.093 0.925–2.785      

*p < 0.05.