Fig. 5.
Endothelial deletion of Rbpj from birth leads to illness and death in P14 mice. (A) Kaplan–Meier survival curve indicating 50% probability of survival for P14 RbpjiΔEC mice. ***P<0.0001. N=24 controls, N=43 mutants. (B) Overall body size was compromised in RbpjiΔEC mice. (C) Total body weight was reduced in P14 RbpjiΔEC mice, but not in P7 RbpjiΔEC mice. P7: P=0.217 (not significant); N=42 controls, N=29 mutants. P14: ***P<0.0001; N=48 controls, N=49 mutants. P-values were according to Student's t-test.