Table 2.
SOX4 response to changing levels of miR-421.
| Sample Name | miR-421 | SOX4 |
|---|---|---|
| CP neo cells | 1.02 ± 0.21 | 1.01 ± 0.18 |
| miR-421 OE | 1.81 ± 0.32 * | 0.63 ± 0.04 * |
| p value | 0.023 | 0.021 |
| TOF cells | 1.00 ± 0.05 | 1.00 ± 0.09 |
| miR-421 KD | 0.27 ± 0.03 * | 1.81 ± 0.14 * |
| p value | 0.004 | 0.011 |
CP neo = Celprogen neonatal cardiomyocytes from normally developing subjects; TOF cells = primary cells derived from the right ventricle of children with tetralogy of Fallot; OE = over expression; KD = knockdown * = significant change relative to starting level.