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Removal of one copy of Bmp4 enhances phenotypic defects in Bmp4S2KHAmyc mutants. (A-D) Bmp4+/lacZ and Bmp4S2K/+ mice were intercrossed, and representative E11.5 embryos from a single litter were stained for β-galactosidase, which marks the Bmp4lacZ allele. (E,F) Embryos from a second litter were photographed without staining at E10.5.
