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. 2014 Oct 15;5:552. doi: 10.3389/fpls.2014.00552

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Copyright © 2014 Araújo, Martins, Fernie and Tohge.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Major enzymatic reactions of 2-ODD involved in GA and plant secondary metabolism. 2-ODDs involved in (A) GA, (B) glucosinolate, (C) flavonoid, (D) tropan alkaloid, (E) isoquinorine biosynthesis are described. GA20ox, GA20-oxidase; GA3ox, GA3β-hydroxylase; GA2ox, GA 2-oxidase; AOP, alkenyl/hydroxy (OH) alkyl producing enzymes; GSL-OH, glucosinolate 2-oxoacid-dependant dioxygenase gene; FS-I, flavone synthase I; FLS, flavonol synthase, F3H, flavanone 3-hydroxylase, ANS, anthocyanin synthase; H6H, hyoscyamine 6-hydroxylase; T6ODM, 6-demethylase; CODM, codeine O-demehtylase.