Table 5.

Age-Related Differences in the Rate of Parameter Change in EG Eyes

	SD-OCT
	Anterior Laminar Depth,* μm/d	BMO Depth, μm/d	Prelaminar Tissue Thickness, μm/d	MRW, μm/d	RNFLT, μm/d
Change/day† in young EG eyes	−0.460	−0.109	0.088	−0.202	−0.004
Change/day† in old EG eyes	−0.102	−0.003	−0.040	−0.099	−0.010
Change rates young vs. old EG eyes, P value‡	<0.0001	<0.0001	<0.0001	0.1433	0.4901
Change rates in EG vs. control eyes: young animals, P value§	<0.0001	0.0002	0.2013	0.0029	0.7957
Change rates in EG vs. control eyes: old animals, P value‖	0.0001	0.6175	0.0186	0.0221	0.3559
Positive change	Anterior to BMO	Anterior to PeriBM	Thickening	Thickening	Thickening
Negative change	Posterior to BMO	Posterior to PeriBM	Thinning	Thinning	Thinning

^*Rates of change were derived from the slope coefficients from the GEE model for each SD-OCT parameter. Bold text indicates P < 0.05, which is statistically significant.

^†The longitudinal change rate of each parameter represents how much the parameter changed for each unit of time (units in day) relative to mean baseline. The data reported here are the mean value for the n = 4 old and n = 4 young EG eyes.

^‡P value for whether the rate of parameter change is significant between young and old EG eyes.

^§P value for whether the rate of parameter change in the EG eye is significantly different from in control eyes in young animals.

‖ P value for whether the rate of parameter change in the EG eye is significantly different from in control eyes in old animals.