Table 2.

Top Molecular and Cellular Functions Significantly Affected in 2- and 4-Month-Old N101D Lenses Relative to WT Lenses as Determined by Ingenuity Pathway Analysis

	P Value	Number of Molecules
2 Months Old
Cellular assembly  and organization	8.50E-07–1.99E-02	292
Cell morphology	1.04E-10–1.62E-02	187
Cellular function  and maintenance	1.33E-10–1.62E-02	183
4 Months Old
Cellular assembly  and organization	8.50E-07–1.99E-02	211
Molecular transport	1.97E-06–1.99E-02	159
Cellular function  and maintenance	1.04E-09–1.62E-02	153